Corticosteroids
Topical corticosteroids are a standard treatment option to decrease inflammation. Because they are often associated with side effects such as atrophy, striae, and telangiectasia, they are not recommended for large lesions or areas of the body that are more susceptible to side effects such as the face. Systemic corticosteroids have reported success in rapidly progressing vitiligo. However, due to adverse effects and inconsistent response, steroid monotherapy has long been viewed as a less than ideal treatment. Studies have found that one can often reap more benefit from these drugs by combining them with phototherapy. For example, a randomized left-right comparison study showed that topical fluticasone combined with UVA phototherapy was better than either alone.
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